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Hemolysis Student’s Name Institution Affiliation Date Hemolysis refers to a situation in which the erythrocytes are destructed in their premature state. The state is referred as hemolytic anaemia in the case where the bone marrow is unable to make up for the erythrocytes loss. Anemia may be on the verge of its severity depending on whether hemolysis takes place gradually or it is an abrupt process. It also depends on the level of the erythrocyte destructions. In most cases, mild hemolysis can be asymptomatic which makes it easier to deal with and proactively assists the patient. However, severe hemolysis is a life-threatening condition that can lead to cardiopulmonary decompensation and angina. Hemolysis can be categorized into two: acquired disorder or hereditary. In any case, the erythrocytes can be destroyed in their early stages before they mature as a result of conditions such us immune destruction of the erythrocytes, abnormal haemoglobin, hypersplenism, erythrocyte enzymatic defects or intrinsic membrane defect among others. Hemolysis can also be termed as an intravascular or extravascular phenomenon. In extravascular, the erythrocytes are damaged mostly in spleen and reticuloendothelial tissues. A good example of extravascular hemolysis is hereditary spherocytosis and hemolytic anaemia. Intravascular hemolysis is seen in hemolytic anaemia (Kato, 2017). Erythrocytes have a lifecycle of 120 days. However, hemolysis affects destroy them before their lifecycle is attained. After their destructions, they are cleared out of the body and new ones generated in the bone marrow. An imbalance may occur when the rate of their destruction supersedes the rate at
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